ISSN : 1301-5680
e-ISSN : 2149-8156
TURKISH JOURNAL OF
THORACIC AND
CARDIOVASCULAR SURGERY
Turkish Journal of Thoracic and Cardiovascular Surgery     
Analysis of pulmonary embolism patients treated with EkoSonicTM endovascular system
Bengü Saylan1, Tayfun Çalışkan1, Kadir Canoğlu1, Ali Ertan Ulucan2, Ahmet Turan Yılmaz2
1Department of Pulmonology, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
2Department of Cardiovascular Surgery, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
DOI : 10.5606/tgkdc.dergisi.2020.19133
Background: The aim of this study was to evaluate the efficacy and the safety of the EkoSonicTM endovascular system applications in patients hospitalized with the diagnosis of intermediate-high-risk pulmonary embolism.

Methods: Between January 2018 and March 2019, a total of 15 patients (7 males, 8 females; mean age 64.7±17.8 years, range, 35 to 90 years) who underwent ultrasound-accelerated thrombolysis using the EkoSonicTM endovascular system for pulmonary embolism were retrospectively analyzed. The diagnosis of pulmonary embolism was made based on pulmonary computed tomography angiography. All patients were evaluated by echocardiography for right ventricular dysfunction and serum levels of troponin I and brain natriuretic peptide were recorded.

Results: The mean arterial blood gas oxygen saturation values of the patients before and after the procedure were 86.3±3.5% and 94.2±2.5%, respectively, indicating a statistically significant difference (p=0.001). The mean partial oxygen pressure values before and after the procedure were 73.3±7.7 mmHg and 90.7±5.0 mmHg, respectively, indicating a statistically significant difference (p=0.001). There was also a statistically significant difference in the mean right ventricular diameter before and after the procedure (p=0.001). The mean pre- and post-procedural pulmonary arterial pressure was 44±7.1 mmHg and 36.3±4.5 mmHg, respectively, indicating a statistically significant difference (p=0.001). Of the patients, 93.7% were free from post-procedural complications.

Conclusion: The EkoSonicTM endovascular system improved right ventricular dysfunction, decreased pulmonary arterial pressure, and improved oxygenation in patients with intermediate-high-risk pulmonary embolism without increasing the risk for bleeding.

Keywords : EkoSonicTM endovascular system, pulmonary embolism, ultrasound-accelerated thrombolysis
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